{"id":21633,"date":"2023-11-16T12:25:05","date_gmt":"2023-11-16T08:25:05","guid":{"rendered":"https:\/\/sheniekimi.ge\/?p=21633"},"modified":"2023-12-21T01:47:49","modified_gmt":"2023-12-20T21:47:49","slug":"covid-19-sars-cov-2-ith-gamotsveulma-daavadebam-gamoitsvia-mnishvnelovani-avadoba-da-sikvdilianoba-mthel-msophlioshi","status":"publish","type":"post","link":"https:\/\/sheniekimi.ge\/ambebi\/covid-19-sars-cov-2-ith-gamotsveulma-daavadebam-gamoitsvia-mnishvnelovani-avadoba-da-sikvdilianoba-mthel-msophlioshi\/","title":{"rendered":"COVID-19, SARS-CoV-2-\u10d8\u10d7 \u10d2\u10d0\u10db\u10dd\u10ec\u10d5\u10d4\u10e3\u10da\u10db\u10d0 \u10d3\u10d0\u10d0\u10d5\u10d0\u10d3\u10d4\u10d1\u10d0\u10db, \u10d2\u10d0\u10db\u10dd\u10d8\u10ec\u10d5\u10d8\u10d0 \u10db\u10dc\u10d8\u10e8\u10d5\u10dc\u10d4\u10da\u10dd\u10d5\u10d0\u10dc\u10d8 \u10d0\u10d5\u10d0\u10d3\u10dd\u10d1\u10d0 \u10d3\u10d0 \u10e1\u10d8\u10d9\u10d5\u10d3\u10d8\u10da\u10d8\u10d0\u10dc\u10dd\u10d1\u10d0 \u10db\u10d7\u10d4\u10da \u10db\u10e1\u10dd\u10e4\u10da\u10d8\u10dd\u10e8\u10d8"},"content":{"rendered":"

\u10e1\u10d0\u10d6\u10dd\u10d2\u10d0\u10d3\u10dd\u10d4\u10d1\u10e0\u10d8\u10d5\u10d8 \u10ef\u10d0\u10dc\u10d3\u10d0\u10ea\u10d5\u10d8\u10e1 \u10d4\u10e5\u10e1\u10de\u10d4\u10e0\u10e2\u10d8, \u10ef\u10d0\u10dc\u10d3\u10d0\u10ea\u10d5\u10d8\u10e1 \u10db\u10e1\u10dd\u10e4\u10da\u10d8\u10dd \u10dd\u10e0\u10d2\u10d0\u10dc\u10d8\u10d6\u10d0\u10ea\u10d8\u10d8\u10e1 \u10d9\u10dd\u10dc\u10e1\u10e3\u10da\u10e2\u10d0\u10dc\u10e2\u10d8, \u10d4\u10e5\u10d8\u10db\u10d8, \u10d0\u10d9\u10e0\u10d4\u10d3\u10d8\u10e2\u10d0\u10ea\u10d8\u10d0 \u10d9\u10d0\u10dc\u10d0\u10d3\u10d0\u10e1 \u10ec\u10d0\u10e0\u10db\u10dd\u10db\u10d0\u10d3\u10d2\u10d4\u10dc\u10d4\u10da\u10d8 \u10e1\u10d0\u10e5\u10d0\u10e0\u10d7\u10d5\u10d4\u10da\u10dd\u10e8\u10d8 \u10d2\u10d8\u10dd\u10e0\u10d2\u10d8 \u10e4\u10ee\u10d0\u10d9\u10d0\u10eb\u10d4 \u10d0\u10db\u10d1\u10dd\u10d1\u10e1, \u10e0\u10dd\u10db COVID19<\/a>-\u10e8\u10d8 RNA-\u10e1 \u10e1\u10ee\u10d5\u10d0\u10d3\u10d0\u10e1\u10ee\u10d5\u10d0 \u10d9\u10d0\u10e2\u10d4\u10d2\u10dd\u10e0\u10d8\u10d0 \u10d0\u10e0\u10e1\u10d4\u10d1\u10dd\u10d1\u10e1.<\/span><\/p>\n

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#COVID19<\/a>-\u10e8\u10d8 RNA-\u10e1 \u10e1\u10ee\u10d5\u10d0\u10d3\u10d0\u10e1\u10ee\u10d5\u10d0 \u10d9\u10d0\u10e2\u10d4\u10d2\u10dd\u10e0\u10d8\u10d0 \u10d0\u10e0\u10e1\u10d4\u10d1\u10dd\u10d1\u10e1. \u10d0\u10e5 \u10d0\u10e0\u10d8\u10e1 \u10d0\u10e0\u10e1\u10d4\u10d1\u10e3\u10da\u10d8 \u10ea\u10dd\u10d3\u10dc\u10d8\u10e1 \u10e8\u10d4\u10ef\u10d0\u10db\u10d4\u10d1\u10d0 \u10d0\u10e0\u10d0\u10d9\u10dd\u10d3\u10d8\u10e0\u10d4\u10d1\u10d8\u10e1 RNA-\u10d4\u10d1\u10d8\u10e1 (ncRNAs) \u10d3\u10d0 #SARSCoV2<\/a> \u10d3\u10d0 \u10e1\u10ee\u10d5\u10d0\u10d3\u10d0\u10e1\u10ee\u10d5\u10d0 ncRNA \u10dd\u10ef\u10d0\u10ee\u10d4\u10d1\u10d8\u10e1 \u10e8\u10d4\u10e1\u10d0\u10ee\u10d4\u10d1 \u10d3\u10d0 \u10db\u10d0\u10d7\u10d8 \u10db\u10d0\u10e0\u10d4\u10d2\u10e3\u10da\u10d8\u10e0\u10d4\u10d1\u10d4\u10da\u10d8 \u10e0\u10dd\u10da\u10d4\u10d1\u10d8\u10e1 \u10e8\u10d4\u10e1\u10d0\u10ee\u10d4\u10d1 #\u10d8\u10dc\u10e4\u10d4\u10e5\u10ea\u10d8\u10d8\u10e1\u10d0<\/a> \u10d3\u10d0 #\u10d3\u10d0\u10d0\u10d5\u10d0\u10d3\u10d4\u10d1\u10d4\u10d1\u10d8\u10e1<\/a> \u10de\u10e0\u10dd\u10d2\u10e0\u10d4\u10e1\u10d8\u10e0\u10d4\u10d1\u10d8\u10e1 \u10d3\u10e0\u10dd\u10e1.<\/span><\/div>\n<\/div>\n
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#RNA<\/a> #\u10d5\u10d8\u10e0\u10e3\u10e1\u10d4\u10d1\u10d8<\/a>, \u10e0\u10dd\u10d2\u10dd\u10e0\u10d8\u10ea\u10d0\u10d0 <\/span>#SARSCoV2<\/a>, \u10e8\u10d4\u10e3\u10eb\u10da\u10d8\u10d0\u10d7 \u10db\u10dd\u10d0\u10ee\u10d3\u10d8\u10dc\u10dd\u10dc \u10e3\u10ef\u10e0\u10d4\u10d3\u10e3\u10da\u10d8 \u10d7\u10d0\u10d5\u10d3\u10d0\u10ea\u10d5\u10d8\u10e1 \u10ea\u10d8\u10e0\u10d9\u10e3\u10db\u10d8\u10e0\u10d4\u10d1\u10d0 \u10e1\u10ee\u10d5\u10d0\u10d3\u10d0\u10e1\u10ee\u10d5\u10d0 \u10db\u10d4\u10e5\u10d0\u10dc\u10d8\u10d6\u10db\u10d4\u10d1\u10d8\u10e1 \u10db\u10d4\u10e8\u10d5\u10d4\u10dd\u10d1\u10d8\u10d7, \u10e0\u10dd\u10db\u10da\u10d4\u10d1\u10d8\u10ea \u10ee\u10e8\u10d8\u10e0\u10d0\u10d3 \u10db\u10dd\u10d8\u10ea\u10d0\u10d5\u10e1 \u10e1\u10de\u10d4\u10ea\u10d8\u10e4\u10d8\u10d9\u10e3\u10e0 \u10e3\u10e0\u10d7\u10d8\u10d4\u10e0\u10d7\u10e5\u10db\u10d4\u10d3\u10d4\u10d1\u10d0\u10e1 \u10e3\u10ef\u10e0\u10d4\u10d3\u10e3\u10da \u10d9\u10dd\u10db\u10de\u10dd\u10dc\u10d4\u10dc\u10e2\u10d4\u10d1\u10d7\u10d0\u10dc. \u10d3\u10d0\u10db\u10d0\u10e2\u10d4\u10d1\u10d8\u10d7, \u10d6\u10dd\u10d2\u10d8\u10d4\u10e0\u10d7\u10d8 \u10d5\u10d8\u10e0\u10e3\u10e1\u10e3\u10da\u10d8 \u10d2\u10d4\u10dc\u10dd\u10db\u10d8, \u10d0\u10e1\u10d4\u10d5\u10d4 \u10e8\u10d4\u10d8\u10eb\u10da\u10d4\u10d1\u10d0 \u10d3\u10d0\u10db\u10e3\u10e8\u10d0\u10d5\u10d3\u10d4\u10e1 \u10e3\u10ef\u10e0\u10d4\u10d3\u10e3\u10da\u10d8 \u10db\u10d4\u10e5\u10d0\u10dc\u10d8\u10d6\u10db\u10d8\u10d7, \u10e0\u10d0\u10d7\u10d0 \u10d2\u10d0\u10db\u10dd\u10d8\u10db\u10e3\u10e8\u10d0\u10d5\u10dd\u10e1 \u10d0\u10e0\u10d0\u10d9\u10dd\u10d3\u10d8\u10e0\u10d4\u10d1\u10e3\u10da\u10d8 <\/span>#RNAs<\/a> (ncRNAs), \u10e0\u10dd\u10db\u10da\u10d4\u10d1\u10e1\u10d0\u10ea \u10e8\u10d4\u10d8\u10eb\u10da\u10d4\u10d1\u10d0 \u10f0\u10e5\u10dd\u10dc\u10d3\u10d4\u10e1 \u10db\u10d0\u10e0\u10d4\u10d2\u10e3\u10da\u10d8\u10e0\u10d4\u10d1\u10d4\u10da\u10d8 \u10e4\u10e3\u10dc\u10e5\u10ea\u10d8\u10d4\u10d1\u10d8. \u10db\u10d0\u10d7 \u10e8\u10dd\u10e0\u10d8\u10e1, \u10db\u10d0\u10e1\u10de\u10d8\u10dc\u10eb\u10d4\u10da\u10d8 ncRNA \u10e2\u10e0\u10d0\u10dc\u10e1\u10d9\u10e0\u10d8\u10de\u10e2\u10dd\u10db\u10d8\u10e1 \u10e1\u10de\u10d4\u10ea\u10d8\u10e4\u10d8\u10d9\u10e3\u10e0\u10d8 \u10d4\u10da\u10d4\u10db\u10d4\u10dc\u10e2\u10d4\u10d1\u10d8 \u10db\u10dd\u10d8\u10ea\u10d0\u10d5\u10e1 <\/span>#microRNAs<\/a> (miRNAs), \u10ee\u10d0\u10dc\u10d2\u10e0\u10eb\u10da\u10d8\u10d5\u10d8 \u10d0\u10e0\u10d0\u10d9\u10dd\u10d3\u10d8\u10e0\u10d4\u10d1\u10d0\u10d3\u10d8 RNA-\u10d4\u10d1\u10d8 (lncRNAs) \u10d3\u10d0 \u10ec\u10e0\u10d8\u10e3\u10da\u10d8 RNA-\u10d4\u10d1\u10d8 (circRNAs), \u10d0\u10e6\u10ec\u10d4\u10e0\u10d8\u10da\u10d8\u10d0, \u10e0\u10dd\u10d2\u10dd\u10e0\u10ea \u10db\u10dc\u10d8\u10e8\u10d5\u10dc\u10d4\u10da\u10dd\u10d5\u10d0\u10dc\u10d8 \u10db\u10dd\u10d7\u10d0\u10db\u10d0\u10e8\u10d4\u10d4\u10d1\u10d8 \u10d5\u10d8\u10e0\u10e3\u10e1\u10e3\u10da\u10d8 \u10e0\u10d4\u10de\u10da\u10d8\u10d9\u10d0\u10ea\u10d8\u10e3\u10e0\u10d8 \u10ea\u10d8\u10d9\u10da\u10d8\u10e1 \u10e0\u10d4\u10d2\u10e3\u10da\u10d0\u10ea\u10d8\u10d0\u10e8\u10d8 \u10d3\u10d0 \u10e3\u10ef\u10e0\u10d4\u10d3\u10e3\u10da\u10d8 <\/span>#\u10d0\u10dc\u10e2\u10d8\u10d5\u10d8\u10e0\u10e3\u10e1\u10e3\u10da\u10d8<\/a> \u10de\u10d0\u10e1\u10e3\u10ee\u10d4\u10d1\u10d8. \u10d0\u10e5 \u10d0\u10e0\u10d8\u10e1 \u10d0\u10e0\u10e1\u10d4\u10d1\u10e3\u10da\u10d8 \u10ea\u10dd\u10d3\u10dc\u10d8\u10e1 \u10e8\u10d4\u10ef\u10d0\u10db\u10d4\u10d1\u10d0 <\/span>#ncRNAs<\/a> \u10d3\u10d0 SARS-CoV-2-\u10d8\u10e1 \u10e8\u10d4\u10e1\u10d0\u10ee\u10d4\u10d1 \u10d3\u10d0 NcRNA-\u10e1 \u10e1\u10ee\u10d5\u10d0\u10d3\u10d0\u10e1\u10ee\u10d5\u10d0 \u10dd\u10ef\u10d0\u10ee\u10d8\u10e1 \u10e3\u10d0\u10ee\u10da\u10d4\u10e1\u10d8 \u10d3\u10d4\u10e2\u10d0\u10da\u10d4\u10d1\u10d8 \u10d3\u10d0 \u10db\u10d0\u10d7\u10d8 \u10db\u10d0\u10e0\u10d4\u10d2\u10e3\u10da\u10d8\u10e0\u10d4\u10d1\u10d4\u10da\u10d8 \u10e0\u10dd\u10da\u10d4\u10d1\u10d8 <\/span>#\u10d8\u10dc\u10e4\u10d4\u10e5\u10ea\u10d8\u10d8\u10e1\u10d0<\/a> \u10d3\u10d0 <\/span>#\u10d3\u10d0\u10d0\u10d5\u10d0\u10d3\u10d4\u10d1\u10d4\u10d1\u10d8\u10e1<\/a> \u10de\u10e0\u10dd\u10d2\u10e0\u10d4\u10e1\u10d8\u10e0\u10d4\u10d1\u10d8\u10e1 \u10d3\u10e0\u10dd\u10e1.<\/span><\/div>\n<\/div>\n
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\"????\"<\/span> miRNA-\u10d4\u10d1\u10d8 \u10d0\u10e0\u10d8\u10e1 \u10db\u10dd\u10d9\u10da\u10d4 \u10db\u10d0\u10e0\u10d4\u10d2\u10e3\u10da\u10d8\u10e0\u10d4\u10d1\u10d4\u10da\u10d8 \u10d0\u10e0\u10d0\u10d9\u10dd\u10d3\u10d8\u10e0\u10d4\u10d1\u10d0\u10d3\u10d8 RNA-\u10d4\u10d1\u10d8, \u10e0\u10dd\u10db\u10da\u10d4\u10d1\u10d8\u10ea \u10ec\u10d0\u10e0\u10db\u10dd\u10d8\u10e5\u10db\u10dc\u10d4\u10d1\u10d0 \u10e1\u10de\u10d4\u10ea\u10d8\u10e4\u10d8\u10e3\u10e0\u10d8 RNA-\u10d8\u10e1 \u10e2\u10e0\u10d0\u10dc\u10e1\u10d9\u10e0\u10d8\u10de\u10e2\u10d4\u10d1\u10d8\u10e1 \u10d4\u10dc\u10d6\u10d8\u10db\u10d0\u10e2\u10e3\u10e0\u10d8 \u10d3\u10d0\u10db\u10e3\u10e8\u10d0\u10d5\u10d4\u10d1\u10d8\u10d7. \u10db\u10d0\u10d7\u10d8 \u10db\u10d0\u10e0\u10d4\u10d2\u10e3\u10da\u10d8\u10e0\u10d4\u10d1\u10d4\u10da\u10d8 \u10e4\u10e3\u10dc\u10e5\u10ea\u10d8\u10d4\u10d1\u10d8 \u10e3\u10ef\u10e0\u10d4\u10d3\u10e3\u10da \u10d3\u10dd\u10dc\u10d4\u10d6\u10d4 \u10ee\u10d3\u10d4\u10d1\u10d0 \u10db\u10d0\u10e0\u10d4\u10d2\u10e3\u10da\u10d8\u10e0\u10d4\u10d1\u10d4\u10da\u10d8 \u10de\u10e0\u10dd\u10e2\u10d4\u10d8\u10dc\u10d4\u10d1\u10d8\u10e1 (RNA-\u10d8\u10d7 \u10d2\u10d0\u10db\u10dd\u10ec\u10d5\u10d4\u10e3\u10da\u10d8 \u10ea\u10d8\u10da\u10d8\u10e1 \u10d9\u10dd\u10db\u10de\u10da\u10d4\u10e5\u10e1\u10d8, \u10d0\u10dc RISC) \u10e0\u10d4\u10d9\u10e0\u10e3\u10e2\u10d8\u10e0\u10d4\u10d1\u10d8\u10d7, \u10e0\u10dd\u10db\u10da\u10d4\u10d1\u10d8\u10ea \u10d9\u10d8\u10d3\u10d4\u10d5 \u10e3\u10e4\u10e0\u10dd \u10db\u10d8\u10d6\u10d0\u10dc\u10e8\u10d4\u10ec\u10dd\u10dc\u10d8\u10da\u10d8\u10d0 mRNA-\u10d4\u10d1\u10d8\u10e1 3 \u2032-UTR \u10d1\u10d0\u10d6\u10d8\u10e1 \u10d9\u10dd\u10db\u10de\u10da\u10d4\u10db\u10d4\u10dc\u10e2\u10d0\u10e0\u10dd\u10d1\u10d8\u10d7, \u10e0\u10d0\u10ea \u10d8\u10ec\u10d5\u10d4\u10d5\u10e1 \u10e0\u10d4\u10de\u10e0\u10d4\u10e1\u10d8\u10e3\u10da \u10d4\u10e4\u10d4\u10e5\u10e2\u10e1 \u10d2\u10d4\u10dc\u10d8\u10e1 \u10d2\u10d0\u10db\u10dd\u10ee\u10d0\u10e2\u10e3\u10da\u10d4\u10d1\u10d0\u10d6\u10d4.<\/span><\/div>\n<\/div>\n
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\"????\"<\/span> lncRNA-\u10d4\u10d1\u10d8 \u10d0\u10e0\u10d8\u10e1 \u10d0\u10e0\u10d0\u10d9\u10dd\u10d3\u10d8\u10e0\u10d4\u10d1\u10d0\u10d3\u10d8 \u10e2\u10e0\u10d0\u10dc\u10e1\u10d9\u10e0\u10d8\u10de\u10e2\u10d4\u10d1\u10d8\u10e1 \u10e4\u10d0\u10e0\u10d7\u10dd \u10dd\u10ef\u10d0\u10ee\u10d8, \u10e0\u10dd\u10db\u10da\u10d4\u10d1\u10d8\u10ea \u10ee\u10d0\u10e1\u10d8\u10d0\u10d7\u10d3\u10d4\u10d1\u10d8\u10d0\u10dc \u10d9\u10dd\u10d3\u10d8\u10e0\u10d4\u10d1\u10d8\u10e1 \u10de\u10dd\u10e2\u10d4\u10dc\u10ea\u10d8\u10d0\u10da\u10d8\u10e1 \u10dc\u10d0\u10d9\u10da\u10d4\u10d1\u10dd\u10d1\u10d8\u10d7, \u10db\u10d0\u10d7\u10d8 \u10e3\u10e4\u10e0\u10dd \u10d3\u10d8\u10d3\u10d8 \u10d6\u10dd\u10db\u10d4\u10d1\u10d8\u10d7 \u10e1\u10ee\u10d5\u10d0 ncRNA-\u10d4\u10d1\u10d7\u10d0\u10dc \u10e8\u10d4\u10d3\u10d0\u10e0\u10d4\u10d1\u10d8\u10d7 (200-\u10d6\u10d4 \u10db\u10d4\u10e2\u10d8 \u10dc\u10e3\u10d9\u10da\u10d4\u10dd\u10e2\u10d8\u10d3\u10d8), \u10d3\u10d0 \u10db\u10d0\u10d7\u10d8 \u10ec\u10d0\u10e0\u10db\u10dd\u10e8\u10dd\u10d1\u10d0 \u10d4\u10e0\u10d7\u10d2\u10e3\u10da\u10d8 \u10e2\u10e0\u10d0\u10dc\u10e1\u10d9\u10e0\u10d8\u10e4\u10ea\u10d8\u10e3\u10da\u10d8 \u10d4\u10e0\u10d7\u10d4\u10e3\u10da\u10d4\u10d1\u10d8\u10d3\u10d0\u10dc. lncRNA-\u10d4\u10d1\u10e1 \u10e8\u10d4\u10e3\u10eb\u10da\u10d8\u10d0\u10d7 \u10d3\u10d0\u10d0\u10e0\u10d4\u10d2\u10e3\u10da\u10d8\u10e0\u10dd\u10dc \u10d2\u10d4\u10dc\u10dd\u10db\u10e3\u10e0\u10d8 \u10d2\u10d0\u10db\u10dd\u10db\u10e3\u10e8\u10d0\u10d5\u10d4\u10d1\u10d8\u10e1 \u10d3\u10d8\u10dc\u10d0\u10db\u10d8\u10d9\u10d0 \u10e5\u10e0\u10dd\u10db\u10d0\u10e2\u10d8\u10dc\u10d8\u10d3\u10d0\u10dc \u10ea\u10d8\u10e2\u10dd\u10de\u10da\u10d0\u10d6\u10db\u10d0\u10db\u10d3\u10d4, \u10eb\u10d8\u10e0\u10d8\u10d7\u10d0\u10d3\u10d0\u10d3 \u10d1\u10d8\u10dd\u10da\u10dd\u10d2\u10d8\u10e3\u10e0\u10d8 \u10d9\u10dd\u10db\u10de\u10da\u10d4\u10e5\u10e1\u10d4\u10d1\u10d8\u10e1 \u10db\u10dd\u10da\u10d4\u10d9\u10e3\u10da\u10e3\u10e0\u10d8 \u10d9\u10d0\u10e8\u10ee\u10da\u10d4\u10d1\u10d8\u10e1 \u10db\u10dd\u10e5\u10db\u10d4\u10d3\u10d4\u10d1\u10d8\u10d7, \u10e0\u10dd\u10db\u10da\u10d4\u10d1\u10d8\u10ea \u10e3\u10e0\u10d7\u10d8\u10d4\u10e0\u10d7\u10e5\u10db\u10d4\u10d3\u10d4\u10d1\u10d0\u10e1 \u10d0\u10db\u10e7\u10d0\u10e0\u10d4\u10d1\u10d4\u10dc \u10de\u10e0\u10dd\u10e2\u10d4\u10d8\u10dc\u10d4\u10d1\u10d7\u10d0\u10dc, \u10d3\u10dc\u10db-\u10d7\u10d0\u10dc \u10d3\u10d0 \u10e1\u10ee\u10d5\u10d0 \u10e0\u10dc\u10db-\u10d8\u10e1 \u10db\u10dd\u10da\u10d4\u10d9\u10e3\u10da\u10d4\u10d1\u10d7\u10d0\u10dc.<\/span><\/div>\n<\/div>\n
\n
\"????\"<\/span> cirRNA-\u10d4\u10d1\u10d8 \u10d9\u10dd\u10d5\u10d0\u10da\u10d4\u10dc\u10e2\u10e3\u10e0\u10d0\u10d3 \u10d3\u10d0\u10ee\u10e3\u10e0\u10e3\u10da\u10d8\u10d0 RNA-\u10e1 \u10db\u10dd\u10da\u10d4\u10d9\u10e3\u10da\u10d4\u10d1\u10d8, \u10e0\u10dd\u10db\u10da\u10d4\u10d1\u10d8\u10ea \u10ec\u10d0\u10e0\u10db\u10dd\u10d8\u10e5\u10db\u10dc\u10d4\u10d1\u10d0 \u10d0\u10e0\u10d0\u10d9\u10d0\u10dc\u10dd\u10dc\u10d8\u10d9\u10e3\u10e0\u10d8 \u10e3\u10d9\u10d0\u10dc\u10d0 \u10db\u10dd\u10d5\u10da\u10d4\u10dc\u10d4\u10d1\u10d8\u10e1 \u10db\u10d8\u10d4\u10e0 \u10d9\u10dd\u10d3\u10d8\u10e0\u10d4\u10d1\u10d8\u10e1\u10d0 \u10d3\u10d0 \u10d0\u10e0\u10d0\u10d9\u10dd\u10d3\u10e3\u10e0\u10d8 \u10e2\u10e0\u10d0\u10dc\u10e1\u10d9\u10e0\u10d8\u10e4\u10ea\u10d8\u10d4\u10d1\u10d8\u10e1\u10d2\u10d0\u10dc. \u10d0\u10db \u10e9\u10d8\u10e0\u10e5\u10dd\u10d5\u10d0\u10dc\u10d8 \u10d2\u10d4\u10dc\u10d4\u10d1\u10d8\u10e1 \u10d2\u10d0\u10d0\u10dc\u10d0\u10da\u10d8\u10d6\u10d4\u10d1\u10d0\u10db \u10d2\u10d0\u10db\u10dd\u10d0\u10d5\u10da\u10d8\u10dc\u10d0, \u10e0\u10dd\u10db \u10d8\u10e1\u10d8\u10dc\u10d8 \u10db\u10dd\u10dc\u10d0\u10ec\u10d8\u10da\u10d4\u10dd\u10d1\u10d3\u10dc\u10d4\u10dc #\u10d0\u10dc\u10d7\u10d4\u10d1\u10d8\u10d7<\/a> \u10d3\u10d0 #\u10d8\u10db\u10e3\u10dc\u10e3\u10e0\u10d8\u10de\u10d0\u10e1\u10e3\u10ee\u10d4\u10d1\u10d8\u10d7<\/a>.<\/span><\/div>\n<\/div>\n
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\"????\"<\/span>https:\/\/www.nature.com\/articles\/s41431-023-01462-1<\/a><\/span><\/div>\n<\/div>\n
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There are different categories of RNA involved in #COVID19<\/a>. Here’s a summary of the current knowledge about non-coding RNAs (ncRNAs) and #SARSCoV2<\/a> and the different ncRNA families and their regulatory roles during #infection<\/a> and #disease<\/a> progression.<\/span><\/div>\n<\/div>\n
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There are different categories of RNA involved in #COVID19<\/a>.<\/span><\/div>\n<\/div>\n
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#RNA<\/a>#viruses<\/a> such as #SARSCoV2<\/a> are flexible in their ability to circumvent cellular defenses through a variety of mechanisms that often involve specific interactions with cellular components. Additionally, some viral genomes can also be processed by cellular machinery to generate non-coding #RNAs<\/a> (ncRNAs) that could have regulatory functions. Among them, specific elements of the host ncRNA transcriptome include #microRNAs<\/a> (miRNAs), long non-coding RNAs (lncRNAs) and circular RNAs (circRNAs), have been described as important players in the regulation of the viral replicative cycle and the cellular #antiviral<\/a> responses. Here’s a summary of the current knowledge about #ncRNAs<\/a> and SARS-CoV-2 and the latest details of the different ncRNA families and their regulatory roles during #infection<\/a> and #disease<\/a> progression.<\/span><\/div>\n<\/div>\n
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\"????\"<\/span> miRNAs are short regulatory non-coding RNAs generated by the enzymatic processing of specific RNA transcripts. Their regulatory functions at the cellular level are exerted by recruiting regulatory proteins (RNA-induced silencing complex, or RISC) which are further targeted to the 3\u2032-UTR of mRNAs by base complementarity, causing a repressive effect on gene expression.<\/span><\/div>\n<\/div>\n
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\"????\"<\/span> lncRNAs are a wide family of non-coding transcripts characterized by their lack of coding potential, their larger sizes when compared to other ncRNAs (more than 200 nucleotides), and their origin from devoted transcriptional units. lncRNAs can regulate the dynamics of the genomic output from chromatin to the cytoplasm, mainly by acting as molecular scaffolds of biological complexes that establish interactions with proteins, DNA, and other RNA molecules.<\/span><\/div>\n<\/div>\n
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\"????\"<\/span> circRNAs are covalently closed RNA molecules generated by non-canonical back-splicing events from coding and non-coding transcripts. Analyzing these circRNA parental genes revealed they were involved with #inflammation<\/a> and #immuneresponses<\/a>.<\/span><\/div>\n<\/div>\n
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\"????\"<\/span>https:\/\/www.nature.com\/articles\/s41431-023-01462-1<\/a><\/span><\/div>\n<\/div>\n<\/div>\n
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\"\u10e8\u10d4\u10d8\u10eb\u10da\u10d4\u10d1\u10d0<\/p>\n

#datashvil<\/a><\/strong><\/span><\/p>\n

#drpkhakadze<\/a><\/strong><\/span><\/p>\n

#<\/a>SheniEkimi.ge<\/a><\/strong><\/span><\/p>\n<\/div>\n<\/div>\n<\/div>\n<\/div>\n<\/div>\n<\/div>\n","protected":false},"excerpt":{"rendered":"

\u10e1\u10d0\u10d6\u10dd\u10d2\u10d0\u10d3\u10dd\u10d4\u10d1\u10e0\u10d8\u10d5\u10d8 \u10ef\u10d0\u10dc\u10d3\u10d0\u10ea\u10d5\u10d8\u10e1 \u10d4\u10e5\u10e1\u10de\u10d4\u10e0\u10e2\u10d8, \u10ef\u10d0\u10dc\u10d3\u10d0\u10ea\u10d5\u10d8\u10e1 \u10db\u10e1\u10dd\u10e4\u10da\u10d8\u10dd \u10dd\u10e0\u10d2\u10d0\u10dc\u10d8\u10d6\u10d0\u10ea\u10d8\u10d8\u10e1 \u10d9\u10dd\u10dc\u10e1\u10e3\u10da\u10e2\u10d0\u10dc\u10e2\u10d8, \u10d4\u10e5\u10d8\u10db\u10d8, \u10d0\u10d9\u10e0\u10d4\u10d3\u10d8\u10e2\u10d0\u10ea\u10d8\u10d0 \u10d9\u10d0\u10dc\u10d0\u10d3\u10d0\u10e1 \u10ec\u10d0\u10e0\u10db\u10dd\u10db\u10d0\u10d3\u10d2\u10d4\u10dc\u10d4\u10da\u10d8 \u10e1\u10d0\u10e5\u10d0\u10e0\u10d7\u10d5\u10d4\u10da\u10dd\u10e8\u10d8 \u10d2\u10d8\u10dd\u10e0\u10d2\u10d8 \u10e4\u10ee\u10d0\u10d9\u10d0\u10eb\u10d4 \u10d0\u10db\u10d1\u10dd\u10d1\u10e1, \u10e0\u10dd\u10db COVID19-\u10e8\u10d8 RNA-\u10e1 \u10e1\u10ee\u10d5\u10d0\u10d3\u10d0\u10e1\u10ee\u10d5\u10d0 \u10d9\u10d0\u10e2\u10d4\u10d2\u10dd\u10e0\u10d8\u10d0 \u10d0\u10e0\u10e1\u10d4\u10d1\u10dd\u10d1\u10e1. #COVID19-\u10e8\u10d8 RNA-\u10e1 \u10e1\u10ee\u10d5\u10d0\u10d3\u10d0\u10e1\u10ee\u10d5\u10d0 \u10d9\u10d0\u10e2\u10d4\u10d2\u10dd\u10e0\u10d8\u10d0 \u10d0\u10e0\u10e1\u10d4\u10d1\u10dd\u10d1\u10e1. \u10d0\u10e5 \u10d0\u10e0\u10d8\u10e1 \u10d0\u10e0\u10e1\u10d4\u10d1\u10e3\u10da\u10d8 \u10ea\u10dd\u10d3\u10dc\u10d8\u10e1 \u10e8\u10d4\u10ef\u10d0\u10db\u10d4\u10d1\u10d0 \u10d0\u10e0\u10d0\u10d9\u10dd\u10d3\u10d8\u10e0\u10d4\u10d1\u10d8\u10e1 RNA-\u10d4\u10d1\u10d8\u10e1 (ncRNAs) \u10d3\u10d0 #SARSCoV2 \u10d3\u10d0 \u10e1\u10ee\u10d5\u10d0\u10d3\u10d0\u10e1\u10ee\u10d5\u10d0 ncRNA \u10dd\u10ef\u10d0\u10ee\u10d4\u10d1\u10d8\u10e1 \u10e8\u10d4\u10e1\u10d0\u10ee\u10d4\u10d1 \u10d3\u10d0 \u10db\u10d0\u10d7\u10d8 \u10db\u10d0\u10e0\u10d4\u10d2\u10e3\u10da\u10d8\u10e0\u10d4\u10d1\u10d4\u10da\u10d8 \u10e0\u10dd\u10da\u10d4\u10d1\u10d8\u10e1 \u10e8\u10d4\u10e1\u10d0\u10ee\u10d4\u10d1 #\u10d8\u10dc\u10e4\u10d4\u10e5\u10ea\u10d8\u10d8\u10e1\u10d0 \u10d3\u10d0 #\u10d3\u10d0\u10d0\u10d5\u10d0\u10d3\u10d4\u10d1\u10d4\u10d1\u10d8\u10e1 \u10de\u10e0\u10dd\u10d2\u10e0\u10d4\u10e1\u10d8\u10e0\u10d4\u10d1\u10d8\u10e1 \u10d3\u10e0\u10dd\u10e1. #RNA #\u10d5\u10d8\u10e0\u10e3\u10e1\u10d4\u10d1\u10d8, \u10e0\u10dd\u10d2\u10dd\u10e0\u10d8\u10ea\u10d0\u10d0 #SARSCoV2, […]<\/p>\n","protected":false},"author":1,"featured_media":21634,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"om_disable_all_campaigns":false,"_monsterinsights_skip_tracking":false,"_monsterinsights_sitenote_active":false,"_monsterinsights_sitenote_note":"","_monsterinsights_sitenote_category":0,"_uf_show_specific_survey":0,"_uf_disable_surveys":false,"footnotes":""},"categories":[1],"tags":[109],"class_list":{"0":"post-21633","1":"post","2":"type-post","3":"status-publish","4":"format-standard","5":"has-post-thumbnail","7":"category-uncategorized","8":"tag-kovidi"},"aioseo_notices":[],"_links":{"self":[{"href":"https:\/\/sheniekimi.ge\/ambebi\/wp-json\/wp\/v2\/posts\/21633","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/sheniekimi.ge\/ambebi\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/sheniekimi.ge\/ambebi\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/sheniekimi.ge\/ambebi\/wp-json\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"https:\/\/sheniekimi.ge\/ambebi\/wp-json\/wp\/v2\/comments?post=21633"}],"version-history":[{"count":1,"href":"https:\/\/sheniekimi.ge\/ambebi\/wp-json\/wp\/v2\/posts\/21633\/revisions"}],"predecessor-version":[{"id":32381,"href":"https:\/\/sheniekimi.ge\/ambebi\/wp-json\/wp\/v2\/posts\/21633\/revisions\/32381"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/sheniekimi.ge\/ambebi\/wp-json\/wp\/v2\/media\/21634"}],"wp:attachment":[{"href":"https:\/\/sheniekimi.ge\/ambebi\/wp-json\/wp\/v2\/media?parent=21633"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/sheniekimi.ge\/ambebi\/wp-json\/wp\/v2\/categories?post=21633"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/sheniekimi.ge\/ambebi\/wp-json\/wp\/v2\/tags?post=21633"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}